#achalasia

• Achalasia — A rare primary motor disorder of the esophagus, characterized by the absence of normal peristalsis in the esophageal body and the defective or incomplete relaxation of the lower esophageal sphincter during swallowing. This neurodegenerative condition leads to food accumulation in the esophagus, causing its progressive dilation, clinically manifesting as dysphagia (difficulty swallowing), regurgitation, retrosternal pain, and weight loss.