#anovarie

• Anovaria — A rare pathological condition or congenital anomaly characterized by the complete structural absence or total underdevelopment of both ovaries in an individual with a female phenotype. This severe anomaly of the reproductive system causes a drastic deficiency of sex hormones (estrogens and progesterone), leading to immediate clinical effects such as primary amenorrhea, failure to achieve puberty, and definitive sterility, requiring endocrine replacement therapy.