#urea cycle

• Ammoniemia — The presence and concentration of ammonia or ammonium ions in the circulating blood. Normally, its level is kept very low through its rapid conversion into urea in the liver; the quantitative determination of amoniemie is crucial for diagnosing severe hepatic insufficiency, advanced cirrhosis, or inborn errors of metabolism within the urea cycle.
• Arginase — A highly crucial hydrolytic enzyme, primarily located in the cytoplasm of hepatocytes, which catalyzes the final phase of the urea cycle. This structural biocatalyst splits arginine into ornithine and urea, facilitating the efficient elimination of toxic ammonia resulting from protein metabolism and thus preventing severe neurological disorders.
• Arginine — A vital semi-essential amino acid for the human body, structurally involved in protein synthesis, ammonia detoxification via the urea cycle, and nitric oxide production. This organic compound plays a crucial role in blood pressure regulation, immune system support, wound healing, and hormone secretion, frequently administered as a dietary supplement in sports nutrition and cardiovascular therapies.