Antimitotic
Definition
Preventing, blocking, or halting mitosis (the process of indirect cell division); a chemotherapeutic medication, cytostatic agent (such as vinca alkaloids or taxanes) utilized in the treatment of malignant tumors. In a clinical sense, it acts structurally by disrupting or excessively stabilizing the mitotic spindle, halting the uncontrolled multiplication of cancer cells.
Bilingual Equivalents
- Antimitotic
- Mitotic inhibitor
Grammatical & Source Details
| Inflection Type | Variable adjective or regular neuter noun with standard grammatical gender and structural plural variations. |
| Formation | Morphological compound combining the protective particle 'anti-' with the standard biological descriptive adjective 'mitotic' (mitotic). |
| Spelling / Pronunciation | [ˌæn.ti.maɪ.ˈtɒt.ɪk] |
| Source | Compendium of International Cancer Therapeutics, Cell Biology, and Cytostatic Protocols |
Contextual Usage Examples
RO: Medicul oncolog a prescris un agent antimitotic puternic pentru a sista proliferarea rapidă a țesutului tumoral malign.
EN: The oncologist prescribed a potent antimitotic agent to halt the rapid proliferation of the malignant tumor tissue.
RO: Această substanță vegetală extrasă din tisa manifestă o activitate antimitotică deosebită în testele de laborator pe culturi celulare.
EN: This plant substance extracted from yew exhibits outstanding antimitotic activity in laboratory tests on cell cultures.
RO: Administrarea unui tratament antimitotic structural necesită monitorizarea constantă a numărului de leucocite din sânge.
EN: Administering a structural antimitotic treatment requires constant monitoring of the leukocyte count in the blood.
Idioms & Phrases
Medicament antimitotic / Antimitotic drug
RO: Substanță chimioterapică citotoxică ce țintește aparatul microtubular celular pentru a bloca mitoza în metafază sau anafază.
EN: A cytotoxic chemotherapeutic substance targeting the cellular microtubular apparatus to block mitosis in metaphase or anaphase.
Efect antimitotic / Antimitotic effect
RO: Oprirea biologică a diviziunii celulare induse de o moleculă, determinând apoptoza celulelor cu rată mare de multiplicare.
EN: The biological arrest of cell division induced by a molecule, triggering apoptosis in cells with a high multiplication rate.
Venin antimitotic structural / Structural spindle poison
RO: Compus chimic (cum este colchicina) utilizat în cercetare pentru a bloca formarea fusului mitotic și a studia cromozomii.
EN: A chemical compound (such as colchicine) utilized in research to block mitotic spindle formation and study chromosomes.
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