Antithyroid
Definition
Diminishing, blocking, or regulating the excessive secretion of thyroid gland hormones; a medication or active substance (such as thiamazole or propylthiouracil) used in the therapy of hyperthyroidism and Graves' disease. These compounds intervene directly in the synthesis of organified iodine or inhibit the coupling of iodotyrosines, thereby reducing thyroxine and triiodothyronine synthesis to restore a state of euthyroidism.
Bilingual Equivalents
- Antithyroid
- Thyroid-suppressing
Grammatical & Source Details
| Inflection Type | Variable adjective with regular morphological mutations based on gender and number. Functions as a neuter noun for drug classes. |
| Formation | Formed through prefixation by combining the oppositional modifier 'anti-' with the anatomical adjective 'tiroidian'. |
| Spelling / Pronunciation | [an.ti.ti.roj.di.ˈan] |
| Source | The Merck Manual of Diagnosis and Therapy and Clinical Endocrinology Standards |
Contextual Usage Examples
RO: Medicul endocrinolog i-a prescris un antitiroidian de sinteză pentru a reduce simptomele de agitație și tahicardie.
EN: The endocrinologist prescribed a synthetic antithyroid agent to reduce the symptoms of agitation and tachycardia.
RO: Efectul terapeutic al acestei substanțe antitiroidiene devine vizibil după câteva săptămâni de tratament continuu.
EN: The therapeutic effect of this antithyroid substance becomes noticeable after several weeks of continuous treatment.
RO: Pacienta a urmat o dietă strictă alături de tratamentul antitiroidian administrat zilnic dimineața.
EN: The patient followed a strict diet alongside the antithyroid treatment administered daily in the morning.
Idioms & Phrases
Antitiroidian de sinteză / Synthetic antithyroid drug
RO: Compus chimic farmaceutic utilizat pe termen lung pentru controlul hormonal în caz de hipersecreție tiroidiană.
EN: A pharmaceutical chemical compound used long-term for hormonal control in cases of thyroid hypersecretion.
Efect antitiroidian advers / Adverse antithyroid effect
RO: Reacție secundară nedorită (cum ar fi leucopenia) apărută în timpul administrării medicației tiroidosupresoare.
EN: An unwanted secondary reaction (such as leukopenia) occurring during the administration of thyroid-suppressing medication.
Tratament antitiroidian preoperator / Preoperative antithyroid treatment
RO: Protocol clinic administrat pentru a aduce pacientul în stare metabolică stabilă înainte de o tiroidectomie.
EN: A clinical protocol administered to bring the patient to a stable metabolic state prior to a thyroidectomy.
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