Atopy
Definition
A hereditary or constitutional predisposition of an individual to develop immediate hypersensitivity (allergic) reactions, mediated by immunoglobulin E (IgE) antibodies, upon contact with common environmental allergens such as pollen, dust, or certain foods. This genetic condition manifests clinically through related disorders including atopic dermatitis, bronchial asthma, allergic rhinitis, or urticaria.
Bilingual Equivalents
- Atopy
- Allergic predisposition
Grammatical & Source Details
| Inflection Type | Feminine noun, singular only, taking standard genitive endings in professional medical lexicons. |
| Formation | Neologistic loanword from French 'atopie', originating from ancient Greek 'atopia' (out of place / unusual state). |
| Spelling / Pronunciation | [a.to.ˈni.e] |
| Source | Lexicon of Clinical Immunology, Pathophysiology, and Pediatric Allergology |
Contextual Usage Examples
RO: Medicul a explicat că această atopie familială crește riscul ca sugarul să dezvolte eczeme pe parcursul primului an de viață.
EN: The doctor explained that this familial atopy increases the risk of the infant developing eczema during the first year of life.
RO: Cercetările moderne arată că această atopie nu este determinată de o singură genă, ci are o cauză poligenică complexă.
EN: Modern research shows that this atopy is not determined by a single gene, but has a complex polygenic cause.
RO: Pacienții care suferă de atopie prezintă o barieră cutanată slăbită, care permite pătrunderea mai ușoară a iritanților.
EN: Patients suffering from atopy present a weakened skin barrier, which allows irritants to penetrate more easily.
Idioms & Phrases
Teren de atopie / Atopic terrain / atopic constitution
RO: Profilul biologic și genetic al unui pacient care îl face vulnerabil la declanșarea manifestărilor alergice succesive.
EN: The biological and genetic profile of a patient that makes them vulnerable to the triggering of successive allergic manifestations.
Manifestare de atopie / Manifestation of atopy / atopic symptom
RO: Oricare dintre episoadele clinice (prurit, rinită, dispnee) care apar ca urmare a activării răspunsului imun mediat de IgE.
EN: Any of the clinical episodes (pruritus, rhinitis, dyspnea) occurring as a result of the activation of the IgE-mediated immune response.
Diagnostic de atopie / Diagnosis of atopy / allergy screening
RO: Procedură medicală bazată pe teste cutanate sau analize de sânge care confirmă prezența hipersensibilității genetice.
EN: A medical procedure based on skin prick tests or blood tests confirming the presence of genetic hypersensitivity.
Latest Contextual News
No recent news found for this topic.