Autoanaphylaxis
Definition
A severe and rare form of anaphylactic-type reaction (acute hypersensitivity) triggered inside the body by its own pathologically modified substances or proteins, acting as autoantigens, without requiring the introduction of an external allergen from the environment.
Bilingual Equivalents
- Autoanaphylaxis
- Endogenous anaphylaxis
Grammatical & Source Details
| Inflection Type | Feminine noun, regular structural plural variations with vocalic changes in Romanian medical nominal declensions. |
| Formation | Biological compound noun prefixing the self-reactive marker onto the standard definition for anaphylaxis. |
| Spelling / Pronunciation | [a.u.to.a.na.fi.lak.ˈsi.e] |
| Source | International Lexicon of Allergy, Serology, and Autoimmune Mechanisms |
Contextual Usage Examples
RO: Cercetătorii au simulat un fenomen de autoanafilaxie pe modele de laborator pentru a analiza eliberarea masivă de histamină.
EN: Researchers simulated an autoanaphylaxis phenomenon on laboratory models to analyze the massive release of histamine.
RO: Spre deosebire de o alergie clasică, această autoanafilaxie este provocată direct de degradarea bruscă a unor proteine native.
EN: Unlike a classical allergy, this autoanaphylaxis is directly caused by the sudden degradation of certain native proteins.
RO: Diagnosticul de autoanafilaxie a fost confirmat după excluderea tuturor factorilor alergeni externi posibili.
EN: The diagnosis of autoanaphylaxis was confirmed after ruling out all possible external allergenic factors.
Idioms & Phrases
Șoc de tip autoanafilaxie / Autoanaphylactic shock
RO: Prăbușire cardiovasculară acută mediată imunologic de anticorpi ce reacționează sever cu elemente proprii ale corpului.
EN: Acute cardiovascular collapse immunologically mediated by antibodies reacting severely with the body's own elements.
Mecanism de autoanafilaxie / Autoanaphylaxis mechanism
RO: Cascadă biochimică patologică ce implică degranularea mastocitelor indusă de complexe imune endogene.
EN: A pathological biochemical cascade involving mast cell degranulation induced by endogenous immune complexes.
Autoanafilaxie experimentală / Experimental autoanaphylaxis
RO: Procedură științifică de laborator utilizată pentru studierea hipersensibilității de tip I indusă de țesuturi modificate termic.
EN: A scientific laboratory procedure used to study type I hypersensitivity induced by thermally altered tissues.
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