Autolytic

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adjective (biology / medicine / histology)

Definition

Pertaining to or involving autolysis; that destroys, decomposes, or digests its own cells or tissues via intracellular enzymes (such as lysosomal ones) released after cell death or during programmed physiological processes. In biochemistry and histopathology, the term describes an intrinsic self-destructive process, essential in necrosis, apoptosis, or in the post-mortem degradation of biological samples that were not fixed properly in time.

Bilingual Equivalents

  • Autolytic
  • Self-digesting

Grammatical & Source Details

Inflection Type Variable adjective adjusting across standard gender and plural boundaries.
Formation Neologistic derivation from the noun 'autoliză' (autolysis) using the adjectival suffix '-itic'.
Spelling / Pronunciation [a.u.to.li.ˈtik]
Source Lexicon of Advanced Histology, Cytology, and Biochemical Reactions

Contextual Usage Examples

RO: După recoltare, fragmentul de ficat a suferit o degradare autolitică rapidă din cauza lipsei de formalină.

EN: After collection, the liver fragment underwent rapid autolytic degradation due to the lack of formalin.

RO: Enzimele autolitice din citoplasmă încep să distrugă membrana celulară imediat ce respirația celulară încetează.

EN: The autolytic enzymes in the cytoplasm begin to destroy the cell membrane as soon as cellular respiration ceases.

RO: Medicul legist a stabilit că modificările autolitice ale organelor interne s-au produs la câteva ore după deces.

EN: The forensic pathologist determined that the autolytic changes in the internal organs occurred a few hours after death.

Idioms & Phrases

Enzimă autolitică / Autolytic enzyme

RO: Catalizator biochimic intern (proteinază, lipază) care, odată eliberat din lizozomi, digeră structura propriei celule gazdă.

EN: An internal biochemical catalyst (proteinase, lipase) which, once released from lysosomes, digests the structure of its own host cell.

Degradare autolitică / Autolytic degradation / autolytic decay

RO: Fenomen de descompunere aseptică a țesuturilor organice sub acțiunea exclusivă a propriilor sucuri celulare.

EN: A phenomenon of aseptic decomposition of organic tissues under the exclusive action of their own cellular juices.

Proces autolitic / Autolytic process / self-digestion loop

RO: Succesiune de reacții chimice autodistructive, activată în mod natural în timpul maturării cărnii sau patologic în necroze.

EN: A succession of self-destructive chemical reactions, activated naturally during meat aging or pathologically in necrosis.

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