#degenerative

• Amyloid — An insoluble protein macromolecular aggregate with a pathological fibrillar structure folded into beta-sheets, which abnormally deposits in the intercellular spaces of various organs and tissues. Although its historical name suggests a resemblance to starch due to its specific staining reaction with iodine, amyloid is composed of conformationally altered proteins and is directly responsible for the onset and progression of amyloidosis and severe neurodegenerative disorders, such as Alzheimer's disease.
• Arteriomalacia — A pathological condition characterized by the abnormal softening and loss of elastic consistency of the arterial walls, caused by the degeneration of connective tissue or the destruction of smooth muscle fibers. This structural phenomenon reduces the vessels' capacity to withstand elevated blood pressure, favoring the appearance of aneurysmal dilations or spontaneous vascular ruptures.
• Arthrosis — A chronic degenerative joint disease characterized by the progressive degradation and gradual destruction of the protective cartilage covering bone ends, accompanied by modifications of the subchondral bone and the formation of marginal bone growths called osteophytes. This pathology, closely linked to natural aging, repeated trauma, or excessive mechanical stress, causes persistent pain, nocturnal joint stiffness, and severe reduction of functional mobility.