#hypersensitivity

• Acroesthesia — An abnormal and pathological increase in tactile, thermal, or painful sensitivity localized exclusively within the body's extremities, manifesting as exaggerated sensations triggered by minor stimuli.
• Allergic — 1. Pertaining to, related to, or caused by an allergy; characterized by an immune system hypersensitivity reaction upon contact with an allergen. 2. (Noun) A person who suffers from an allergy, presenting an exaggerated immunological sensitivity to certain environmental substances or foods. 3. (Colloquial) Manifesting a strong aversion, rejection, or deep intolerance toward a situation, a person, or a concept.
• Allergy — A state of pathological hypersensitivity of the immune system, acquired through repeated contact with certain foreign substances (allergens) that are normally harmless to most people. From a structural and molecular standpoint, the reaction involves the massive release of histamine and other inflammatory mediators, manifesting clinically through respiratory, cutaneous, digestive, or vascular symptoms.
• Anaphylaxis — A state of acute, systemic, and violent allergic hypersensitivity of the body, structurally occurring upon the introduction of a foreign substance (antigen) to which the body was previously sensitized. This severe immunological phenomenon involves massive mast cell degranulation and can rapidly progress to circulatory shock, obstructive laryngeal edema, and cardio-respiratory arrest, requiring immediate emergency medical care.
• Autoanaphylaxis — A severe and rare form of anaphylactic-type reaction (acute hypersensitivity) triggered inside the body by its own pathologically modified substances or proteins, acting as autoantigens, without requiring the introduction of an external allergen from the environment.