#skeletal pathology

• Acromicria — A rare pathological clinical condition, considered the opposite of acromegaly, characterized by the unusually small size and insufficient development of the body's extremities (hands, feet, facial bones). This structural syndrome is most often caused by congenital pituitary dysfunctions, diencephalic lesions, or severe secretory disorders of trophic hormones during growth.
• Acropathy — A general medical term or broad clinical category designating any organic, trophic, destructive, or deforming condition localized exclusively in the distal extremities of the body (hands, feet, digits). This structural manifestation can have vascular, neurological, or endocrine causes, including within its scope diverse pathologies from acropachy and neuropathic trophic ulcerations to severe secondary osteoarticular deformities.
• Acro-osteolysis — A destructive pathological process characterized by the progressive bone resorption, decalcification, or dissolution of the terminal (distal) phalanges of the fingers and toes. This severe skeletal structural phenomenon can be congenital or acquired, observed on X-rays as a shortening or disappearance of the phalangeal tufts, and is encountered as a major symptom in systemic sclerosis, secondary hyperparathyroidism, occupational chronic exposure to vinyl chloride, or rare genetic syndromes (such as Hajdu-Cheney syndrome).
• Anostosis — A pathological condition or structural developmental anomaly characterized by the absence, cessation, or congenital defect in the formation and welding of the bony skeleton or a joint; a lack of the normal physiological process of ossification. In a narrow clinical sense, the term defines the structural failure of a fracture to heal or a massive delay in the fusion of the epiphyses with the diaphysis, affecting locomotor biomechanics.