Anostosis
Definition
A pathological condition or structural developmental anomaly characterized by the absence, cessation, or congenital defect in the formation and welding of the bony skeleton or a joint; a lack of the normal physiological process of ossification. In a narrow clinical sense, the term defines the structural failure of a fracture to heal or a massive delay in the fusion of the epiphyses with the diaphysis, affecting locomotor biomechanics.
Bilingual Equivalents
- Anostosis
- Bone non-union
Grammatical & Source Details
| Inflection Type | Feminine noun with regular structural plural and case modifications. |
| Formation | Scholarly clinical compounding from the Greek privative prefix 'an-' (without) + 'osteon' (bone) + the pathological suffix '-osis'. |
| Spelling / Pronunciation | [a.nos.ˈto.zə] |
| Source | Rockwood and Green's Fractures in Adults and Children |
Contextual Usage Examples
RO: Examenul radiologic a evidențiat o anostoză completă la nivelul focarului de fractură, în ciuda fixării metalice.
EN: The radiological examination revealed a complete anostosis at the fracture site, despite the metallic fixation.
RO: Această formă rară de anostoză congenitală împiedică scurtarea sau alungirea fiziologică a membrelor inferioare la copii.
EN: This rare form of congenital anostosis prevents the physiological shortening or lengthening of the lower limbs in children.
RO: Tratamentul pentru o anostoză cronică poate include grefarea de țesut osos autolog pentru a stimula regenerarea.
EN: The treatment for a chronic anostosis may include autologous bone tissue grafting to stimulate regeneration.
Idioms & Phrases
Anostoză congenitală / Congenital anostosis
RO: Defect structural apărut în timpul ontogenezei intrauterine, caracterizat prin incapacitatea celulelor de a sintetiza matricea minerală.
EN: A structural defect occurring during intrauterine ontogenesis, characterized by the cells' inability to synthesize the mineral matrix.
Focar de anostoză / Anostosis site
RO: Zonă anatomică delimitată unde procesul de consolidare a țesutului osos s-a oprit definitiv din cauze vasculare.
EN: A delimited anatomical area where the bone tissue consolidation process has stopped permanently due to vascular causes.
Anostoză post-traumatică / Post-traumatic anostosis
RO: Complicație chirurgicală severă manifestată prin lipsa formării calusului după o intervenție de osteosinteză.
EN: A severe surgical complication manifested by the lack of callus formation following an osteosynthesis procedure.
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